Ribosomal protein L11 methyltransferase



Ribosomal protein L11 methyltransferase (L11 MTase) catalyzes the methylation of ribosomal protein L11 (RPL11). The images at the left and at the right correspond to one representative L11 MTase, i.e. the crystal structure of Apo-form of Thermus thermophilus ribosomal protein L11 methyltransferase (2nxc).

L11 MTase
3grz – L11 MTase C-terminal – Lactobacillus delbruekii

2nxc, 2nxj - TtL11 MTase - Thermus thermophilus

2zbp, 2zbq, 2zbr, 2nxe– TtL11 MTase+S-adenosyl derivatives

L11 Mtase+RPL11
3egv, 2nxn – TtL11 Mtase+RPL11

3cjq - TtL11 Mtase+RPL11 (mutant)

3cjr - TtL11 Mtase+RPL11 (mutant)+sinefungin

3cjs - TtL11 Mtase N-terminal+RPL11 N-terminal

3cjt - TtL11 Mtase (mutant)+RPL11